Medicina· 2026Q2
Dorsal Onlay Bukkal Mukoza Greft Üretroplasti, Kadın Üretra Darlığında Yüksek Başarı Gösterdi
Early Outcomes of Dorsal Onlay Buccal Mucosal Graft Urethroplasty for Female Urethral Stricture Disease: A Single-Center Experience
- 0atıf
- Q2SCImago
- 2026yıl
Kısa özet
Dorsal onlay bukkal mukoza greft üretroplasti (DO-BMGU), kadın üretra darlığı (FUS) olan 20 kadında, ortalama 12 aylık takipte %90 oranında yeniden müdahale gerektirmeme başarısı gösterdi.
Yapay zekâ ile başlık ve abstract'tan üretildi; tam metin okunmaz.
Ana noktalar
- FUS'lu 20 kadının %90'ı, ortalama 12 aylık takip sonunda DO-BMGU sonrası semptomatik nüks nedeniyle yeniden müdahaleden uzak kaldı.
- Ortalama idrar akış hızı (Qmax) 6.1'den 20.4 mL/s'ye, post-void rezidü idrar ise 125 mL'den 10 mL'ye düştü.
- Ortalama operasyon süresi 65 dakika, ortalama hastanede kalış süresi ise 3 gün olarak saptandı.
- Sadece bir hastada (%5) hafif de novo stres üriner inkontinans gelişti; majör kanama veya fistül görülmedi.
Yapay zekâ ile başlık ve abstract'tan üretildi; tam metin okunmaz.
Özet (abstract)
Background and Objectives: To evaluate the surgical, functional, and perioperative outcomes of Dorsal Onlay Buccal Mucosal Graft Urethroplasty (DO-BMGU) in women with Female urethral stricture (FUS) disease. Material and Methods: A retrospective analysis was performed including women who underwent DO-BMGU for FUS at a single tertiary referral center between January 2018 and October 2025. The primary outcome was freedom from reintervention for symptomatic recurrence. Secondary outcomes included perioperative outcomes, complications, and changes in maximum urinary flow rate (Qmax) and postvoid residual urine volume (PVR). Results: Twenty women with a mean age of 52.9 ± 14.7 years were included. The median stricture length was 2 cm (IQR 2–3), and all patients had undergone previous urethral dilatation. Median operative time was 65 min (IQR 60–80), with a median hospital stay of 3 days (IQR 3–4). During a median follow-up of 12 months (IQR 12–24), 18 patients (90%) remained free from reintervention for symptomatic recurrence. Two patients developed recurrent symptomatic narrowing and were successfully managed with urethral dilatation. At the 3-month objective functional assessment, mean Qmax improved significantly from 6.1 ± 2.3 to 20.4 ± 5.8 mL/s (p < 0.001), while median PVR decreased from 125 mL (IQR 94.5–155) to 10 mL (IQR 10–40) (p < 0.001). No patient experienced major bleeding or urethrovaginal fistula. One patient (5%) developed mild de novo stress urinary incontinence, and postoperative complications were generally minor and managed conservatively. Conclusions: DO-BMGU was associated with favorable early objective functional outcomes and a high rate of freedom from reintervention for symptomatic recurrence, with few clinically significant complications in this small cohort. Larger prospective studies with longer follow-up are warranted to confirm the long-term durability of this technique.
Yazarların özeti; kaynağından alınmıştır. Medicina, 2026 · DOI ↗
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