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Annals of Neurology· 2026Q1

Activated Fibroblast Imaging in Baló's Concentric Sclerosis

Amélie Castiaux, Sophie Elands, Xavier De Tiège, Gil Leurquin‐Sterk

Short summary

This study introduces a novel PET imaging technique to visualize activated fibroblasts in Baló's concentric sclerosis (BCS) lesions.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Developed a PET imaging technique using [18F]FB-GTP to detect activated fibroblasts.
  • Visualized fibroblast activation in active Baló's concentric sclerosis (BCS) lesions.
  • Fibroblast activation correlated with disease activity in BCS.
  • Imaging may offer a tool to monitor therapeutic interventions in BCS.

AI-generated from the title and abstract; the full text is not read.

Abstract

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The data used during the current manuscript is available from the corresponding author on reasonable request and after approval by institutional authorities (Université libre de Bruxelles & Hôpital Universitaire de Bruxelles).

The authors' abstract, as published at the source. Annals of Neurology, 2026 · DOI ↗

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine