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BMC Urology· 2026Q2

Retrospective study on the characteristics of common sexually transmitted infections in urogenital tract pathogens in Beijing

Meimei Zhao, Yongwei Jiang, 孔晓牧, Yi Liu et al.

Short summary

Ureaplasma urealyticum (UU) is the predominant urogenital pathogen in Beijing, with overall detection rates of 21.99% (1621/7373), significantly higher than Mycoplasma genitalium (2.70%), Chlamydia trachomatis (3.76%), and Neisseria gonorrhoeae (1.84%) across 7,373 patient samples.

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Key points

  • Ureaplasma urealyticum (UU) was the most prevalent pathogen, with an overall detection rate of 21.99% in 7,373 patient samples.
  • UU infection rates were significantly higher in females (55.02%) than in males (16.16%).
  • Neisseria gonorrhoeae infection rates were higher in males (1.99%) than in females (1.00%).
  • Mycoplasma genitalium and Chlamydia trachomatis had lower overall detection rates of 2.70% and 3.76%, respectively.

AI-generated from the title and abstract; the full text is not read.

Abstract

This study aims to investigate the infection status of Mycoplasma genitalium (MG), Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Ureaplasma urealyticum (UU) among male and female patients in Beijing, thereby providing a foundation for clinical diagnosis and treatment. A comprehensive collection of 7,373 urine, urethral swab, and cervical swab samples was obtained from male and female patients attending the China-Japan Friendship Hospital between December 2019 and March 2024. The detection of MG-RNA, CT-RNA, NG-RNA, and UU-RNA was performed using simultaneous amplification and testing (SAT). Subsequently, the infection status was analyzed across different variables, including sex, age, and diagnosis. The overall positive detection rates for MG, CT, NG, and UU among all patients were 2.70% (199/7373), 3.76% (277/7373), 1.84% (136/7373), and 21.99% (1621/7373), respectively. Notably, the detection rate of UU was significantly higher compared to the other three pathogens, with the difference being statistically significant ( P < 0.01). Among male patients, the infection rates for MG, CT, NG, and UU were 2.76% (173/6268), 3.72% (233/6268), 1.99% (125/6268), and 16.16% (1013/6268), respectively. In females, the infection rates for MG, CT, NG, and UU were 2.35% (26/1105), 3.98% (44/1105), 1.00% (11/1105), and 55.02% (608/1105), respectively. The infection rate of UU in females was significantly higher than in males, whereas the infection rate of NG was higher in males than in females. These differences were statistically significant ( P < 0.05). UU is the predominant infection of the urogenital tract in both male and female patients in the Beijing area. Therefore, it is imperative to enhance early screening and monitoring in clinical diagnosis and treatment, and to initiate early clinical intervention.

The authors' abstract, as published at the source. BMC Urology, 2026 · DOI ↗

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MicrobiologyImmunology and Microbiology