Annals of Surgical Oncology· 2026Q1
Pegulicianine Kılavuzluğunda Yapılan Meme Cerrahisinde Ek Marjin Çıkarılması Hasta Memnuniyetini Azaltmıyor
Does Additional Margin Excision During Pegulicianine Fluorescence-Guided Surgery (pFGS) Affect Patient Breast Satisfaction?
- 1atıf
- Q1SCImago
- 2026yıl
Kısa özet
Pegulicianine floresan kılavuzluğunda cerrahi (pFGS) ile ek marjin çıkarılan meme kanseri lumpektomi hastalarında, standart lumpektomiye kıyasla meme memnuniyetinde anlamlı bir düşüş gözlenmedi (ortalama skor 75.8'e karşı 79.0, p=0.53).
Yapay zekâ ile başlık ve abstract'tan üretildi; tam metin okunmaz.
Ana noktalar
- Ek marjin çıkarılan pFGS (75.8) ve standart lumpektomi (79.0) uygulanan hastalar arasında meme memnuniyeti skorları benzerdi.
- Ek pFGS destekli kavite marjinleri alınan hastaların ortalama memnuniyet skoru 73.6 iken, ek doku alınmayanlarda bu skor 78.5 idi.
- Hastaların %70.6'sı, kozmetik sonuçları optimize etmeye kıyasla ikinci bir ameliyattan kaçınmayı tercih etti.
- Ek doku çıkarılmasına rağmen pFGS sırasında meme memnuniyetinde bir azalma gözlenmedi.
Yapay zekâ ile başlık ve abstract'tan üretildi; tam metin okunmaz.
Özet (abstract)
BACKGROUND: Use of pegulicianine fluorescence-guided surgery (pFGS) for intraoperative residual tumor assessment in breast cancer lumpectomy surgery removed additional tumor and reduced second surgeries. This study assessed breast satisfaction among patients with and without additional margin excision and preference for optimizing cosmesis versus avoiding a second surgery. METHODS: Two clinical trials randomized stages 0 to 3 breast cancer patients to pFGS or standard lumpectomy. For pFGS, additional cavity margin specimens were taken at sites of pegulicianine fluorescence after standard lumpectomy. Surveys of BREAST-Q satisfaction were administered in trials 1 and 2, and surveys of cancer worry and patient preference information (PPI) were administered in trial 2. RESULTS: Satisfaction surveys were completed 6 to 12 months postoperatively by 14 % of the trial 1 and 67 % of the trial 2 patients. The mean postoperative breast satisfaction score was 75.8 (n = 99; range, 15-100) for the pegulicianine-assisted arm patients versus 79.0 (n = 19; range, 35-100) for the control subjects (p = 0.53). The mean breast satisfaction score was 73.6 (n = 52; range, 33-100) among the patients with additional pFGS-assisted cavity margins taken versus 78.5 (n = 66; range, 15-100) (p = 0.17) among those with no additional tissue taken. Overall, 70.6 % of the respondents strongly preferred or preferred avoiding a second surgery, 19.6 % had no preference, and only 9.8 % preferred to optimize cosmetic outcomes. No patient strongly preferred to optimize cosmetic outcomes CONCLUSIONS: No decrease in breast satisfaction was observed among the breast cancer lumpectomy patients undergoing pFGS intraoperative margin assessment despite additional tissue removal. Most of the patients valued avoiding a second surgery over maximizing cosmetic outcome.
Yazarların özeti; kaynağından alınmıştır. Annals of Surgical Oncology, 2026 · DOI ↗
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