The Journal of Strength and Conditioning Research· 2022Q1
Simüle Edilmiş Amerikan Futbolu Oyunu Hafızayı Bozuyor ve İnflamatuar Belirteçleri Değiştiriyor
Examination of Cognitive Function, Neurotrophin Concentrations, and both Brain and Systemic Inflammatory Markers Following a Simulated Game of American Football
- 6atıf
- Q1SCImago
- 2022yıl
Kısa özet
Simüle edilmiş bir Amerikan futbolu oyunu, oyun sonrası hemen akut hafızada anlamlı düşüşlere (p < 0.001) ve gecikmiş hafızada düşüş eğilimine (p = 0.066) neden oldu, bilişsel fonksiyon 24 saat içinde normale döndü. Oyun süresi, konsantrasyon değişiklikleriyle olumsuz yönde ilişkiliydi.
Yapay zekâ ile başlık ve abstract'tan üretildi; tam metin okunmaz.
Ana noktalar
- Oyun sonrası hemen akut hafıza anlamlı şekilde azaldı (p < 0.001).
- Oyun süresi, hafıza konsantrasyonu değişiklikleriyle olumsuz korelasyon gösterdi (r = -0.801, p = 0.001).
- Sistemik inflamatuar belirteçler (TNF-α, BDNF, CRP) oyun sonrası arttı.
- Linemenlar, beceri oyuncularına kıyasla artmış dolaşan CRP ve sitokin belirteçleri (IL-4, IL-6, IL-10, TNF-α) sergiledi.
- Beyin hasarı belirteçlerinde (S100B, GFAP, tau) veya kas hasarı belirteçlerinde (miyoglobin, CK-MM) anlamlı artış gözlenmedi.
Yapay zekâ ile başlık ve abstract'tan üretildi; tam metin okunmaz.
Özet (abstract)
ABSTRACT: Hoffman, JR, Ostfeld, I, Zamir, A, Amedi, R, Fonville, TR, Horstemeyer, MF, and Gepner, Y. Examination of cognitive function, neurotrophin concentrations, and both brain and systemic inflammatory markers following a simulated game of American football. J Strength Cond Res 36(3): 686-694, 2022-This investigation examined the effect of a simulated American football game on cognitive function, neurotrophin concentrations, and markers of both systemic and brain inflammation. Members of the Israel national team (6 linemen and 9 skill position players) were examined 1 week before (PRE), immediately post (IP) and 24-hour post (24P) game. Blood was obtained, and cognitive function was measured at each assessment. No head injuries to any of the players participating in the study occurred. Significant (p < 0.001) decreases in acute memory, and a trend (p = 0.066) toward a decrease in delayed memory was noted at IP. Significant negative correlations were observed between playing time (number of plays) and concentration changes from PRE to IP (r = -0.801; p = 0.001) and from PRE to 24P (r = -0.549; p = 0.034). All cognitive function measures returned to PRE levels by 24P. Increases from PRE were noted in tumor necrosis factor-alpha (TNF-α) (p = 0.041) at IP and in brain-derived neurotrophic factor (p = 0.009) and C-reactive protein (CRP) (p = 0.019) concentrations at 24P. Circulating CRP concentrations and the cytokine markers, interleukin (IL)-4, IL-6, IL-10, and TNF-α, were significantly elevated in linemen compared with skill players. Brain inflammatory markers (S100B and glial fibrillary acidic protein) and total tau protein (a marker of brain injury) were not elevated from PRE. No change from PRE was noted in either myoglobin or creatine kinase-MM concentrations. In conclusion, muscle damage and inflammatory marker responses observed from the scrimmage game were consistent with muscle desensitization associated with football participation. In addition, the systemic inflammatory marker results observed in linemen were suggestive of chronic low-grade inflammation.
Yazarların özeti; kaynağından alınmıştır. The Journal of Strength and Conditioning Research, 2022 · DOI ↗
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