Labrador Retrieverlarda Sahipler Tarafından Bildirilen Cilt Semptomlarının Yaşa Bağlı Kalıtılabilirliği ve Islah Stratejileri İçin Etkileri

Özet (abstract)

Objectives In decentralised breeding programmes, consistent health monitoring can be challenging, yet accurate phenotyping is essential for informed selection. This study evaluated whether a concise owner‐based online survey could capture clinically relevant dermatologic signs in a Belgian assistance‐dog breeding population, and whether the resulting phenotypes could support breeding decisions. Materials and Methods Survey data were collected between June 2024 and October 2025 from 223 Labrador retrievers (median age 2.1 years, range 11 months to 8 years). Owners reported the frequency of otitis externa, general itch, paw biting, skin redness and bald spots, recoded into ordinal symptom scores and summed into a total symptom score. Analyses were performed for the full population and by age group (younger vs. older than 3 years). Results Overall, 38% of dogs had a non‐zero total symptom score. Confirmed canine atopic dermatitis was associated with markedly higher scores (rate ratio = 9.3, 95% CI = 7.2 to 11.9). Each one‐point increase in combined parental score corresponded to approximately 9% higher expected offspring score (rate ratio = 1.09, 95% CI = 1.06 to 1.12). Overall heritability was 0.52 (95% highest posterior density 0.24 to 0.75), with substantial age‐related variation: h 2 = 0.05 in dogs under 3 years and h 2 = 0.81 in dogs aged 3 years or older. Clinical Significance A brief owner‐based survey can generate semi‐quantitative dermatological phenotypes associated with confirmed disease and familial risk. Symptom expression in younger dogs showed low heritability, which may reflect incomplete phenotype expression at this age but could also result from environmental influences, whereas phenotypes in older dogs seem to more strongly reflect genetic predisposition, suggesting later‐life records may better support selection decisions in decentralised breeding programmes.

Yazarların özeti; kaynağından alınmıştır. Journal of Small Animal Practice, 2026 · DOI ↗