Nitrik Oksit'in Ultra Hassas ve Yüksek Seçici Fotoelektrokimyasal Tespiti İçin UiO-66 Yüzey Modifiye CuPc/SrTiO3 Heteroyapı Fotoelektrodu

Özet (abstract)

Abstract Nitric oxide (NO) is an important gaseous signaling molecule involved in vascular regulation, neural transmission, and immune responses. However, its short lifetime, low steady-state concentration, and dynamic release behavior make real-time in situ monitoring challenging, particularly in phototriggered NO release systems. Herein, a dual-functional photoelectrochemical (PEC) platform was developed by integrating a UiO-66 surface layer with a CuPc/SrTiO3 heterojunction photoelectrode for simultaneous NO detection and dynamic monitoring of nitroglycerin-triggered NO release. The CuPc/SrTiO3 heterojunction promotes photogenerated charge separation, while the UiO-66 layer enriches NO through abundant Zr–O active sites, enhancing the interfacial response. Under illumination, nitroglycerin releases NO while the photoelectrode generates a stable photocurrent. The released NO consumes photogenerated holes, producing a concentration-dependent photocurrent decrease, enabling real-time kinetic analysis. The PEC platform exhibited a linear range of 0.063–10 nM, a detection limit of 0.019 nM (S/N = 3), and a quantification limit of 0.063 nM (S/N = 10), with good selectivity, stability, and reproducibility. The platform also enabled continuous monitoring of nitroglycerin-induced NO release in a simulated physiological environment, providing a PEC-based strategy for investigating photoinduced gas generation and release kinetics.

Yazarların özeti; kaynağından alınmıştır. Analytical Chemistry, 2026 · DOI ↗