The Annual Review of Pharmacology and Toxicology· 2026Q1· Review
Pharmacological Individuality: The Twists and Turns of My Journey
- 0citations
- Q1SCImago
- 2026year
Short summary
This review chronicles a physician-scientist's career focused on understanding individual variations in drug response, contributing to the rise of pharmacogenomics and personalized medicine.
AI-generated from the title and abstract; the full text is not read.
Key points
- The author's research was motivated by the observed large individual variations in patient responses to drug therapy.
- Key research areas included identifying genetic, environmental, and other influences on drug response individuality.
- The ultimate goal was to predict drug responses and optimize therapy for individual patients.
- The work has contributed to the emergence of pharmacogenomics, personalized medicine, and precision medicine.
AI-generated from the title and abstract; the full text is not read.
Abstract
The intent of this review is a nearly chronicle tale of my life as a physician-scientist, recounting the events, fortuitous encounters, and sites that shaped my career. Intrigued as a clinician by the large individual variation in response to drug therapy, my research efforts centered on finding the causes for this individuality, including genetic, environmental, and other influences. The ultimate goal was to better predict drug responses in an individual patient and allow decisions on drug choice and drug dose to optimize the clinical outcomes of therapies. The results of my research have contributed to the emergence of pharmacogenomics, personalized medicine, and precision medicine.
The authors' abstract, as published at the source. The Annual Review of Pharmacology and Toxicology, 2026 · DOI ↗
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Field: Pharmacology (Pharmacology, Toxicology and Pharmaceutics)
PharmacologyPharmacology, Toxicology and Pharmaceutics