World Psychiatry· 2014Q1
Risks of all-cause and suicide mortality in mental disorders: a meta-review
- 2,121citations
- Q1SCImago
- 2014year
Short summary
Mental disorders are associated with a 10-20 year reduction in life expectancy due to increased all-cause mortality, comparable to heavy smoking.
AI-generated from the title and abstract; the full text is not read.
Key points
- All mental disorders are linked to increased all-cause mortality compared to the general population.
- Mortality risks for many mental disorders are comparable to or greater than heavy smoking.
- Substance use disorders and anorexia nervosa have the highest all-cause mortality ratios.
- Mental disorders can reduce life expectancy by 10-20 years.
- Borderline personality disorder, anorexia nervosa, depression, and bipolar disorder have the highest suicide risks.
AI-generated from the title and abstract; the full text is not read.
Abstract
A meta-review, or review of systematic reviews, was conducted to explore the risks of all-cause and suicide mortality in major mental disorders. A systematic search generated 407 relevant reviews, of which 20 reported mortality risks in 20 different mental disorders and included over 1.7 million patients and over a quarter of a million deaths. All disorders had an increased risk of all-cause mortality compared with the general population, and many had mortality risks larger than or comparable to heavy smoking. Those with the highest all-cause mortality ratios were substance use disorders and anorexia nervosa. These higher mortality risks translate into substantial (10-20 years) reductions in life expectancy. Borderline personality disorder, anorexia nervosa, depression and bipolar disorder had the highest suicide risks. Notable gaps were identified in the review literature, and the quality of the included reviews was typically low. The excess risks of mortality and suicide in all mental disorders justify a higher priority for the research, prevention, and treatment of the determinants of premature death in psychiatric patients.
The authors' abstract, as published at the source. World Psychiatry, 2014 · DOI ↗
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Field: Clinical Psychology
Clinical PsychologyPsychology