Pediatric Dermatology· 2026Q2
Impact of Biologic Therapy on Emergency Department Utilization in Pediatric Hidradenitis Suppurativa Patients
- 0citations
- Q2SCImago
- 2026year
Short summary
Biologic therapy in pediatric patients with hidradenitis suppurativa (HS) was associated with a 39% reduction in all-cause emergency department (ED) visits within 5 years of treatment initiation (RR: 0.61, 95% CI: 0.48-0.77; NNT, 10).
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Key points
- Biologic therapy in pediatric HS patients reduced all-cause ED visits by 39% at any time after treatment initiation (RR: 0.61, p < 0.0001).
- The number needed to treat (NNT) to prevent one ED visit was 10.
- Reduced ED utilization was observed at 5 years (RR: 0.75, p=0.0250) and 10 years (RR: 0.65, p=0.0002) post-treatment initiation.
- The study compared pediatric HS patients receiving biologics to biologic-naïve controls.
AI-generated from the title and abstract; the full text is not read.
Abstract
Hidradenitis suppurativa (HS) is a chronic inflammatory condition that often begins in adolescence and is associated with substantial morbidity and increased healthcare utilization, including emergency department (ED) visits. Using the TriNetX Global Network, a retrospective cohort study was conducted comparing pediatric HS patients who received biologic therapy before adulthood with biologic-naïve pediatric HS controls. Biologic exposure was associated with a lower cumulative incidence of 1 or more all-cause ED visits at 5 years (RR: 0.75, 95% CI: 0.58-0.97; p = 0.0250), 10 years (RR: 0.65, 95% CI: 0.51-0.84; p = 0.0002), and at any time after index (RR: 0.61, 95% CI: 0.48-0.77; p < 0.0001; NNT, 10). These findings suggest that biologic exposure during pediatric years is associated with lower subsequent all-cause ED utilization among patients with HS.
The authors' abstract, as published at the source. Pediatric Dermatology, 2026 · DOI ↗
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Field: Dermatology
DermatologyMedicine