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Annals of Internal Medicine· 2020Q1

Attitudes Toward a Potential SARS-CoV-2 Vaccine

Kimberly A. Fisher, Sarah J. Bloomstone, Jeremy Walder, Sybil L. Crawford et al.

Short summary

A US national survey (n≈1000) in April 2020 found 30% of adults were unsure and 10% intended not to get a COVID-19 vaccine, with hesitancy linked to younger age, Black race, lower education, and prior flu vaccine non-receipt.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Approximately 30% of US adults were unsure about getting a COVID-19 vaccine, and 10% intended not to get vaccinated in April 2020.
  • Vaccine hesitancy was independently associated with younger age, Black race, lower educational attainment, and not receiving the prior year's influenza vaccine.
  • Key reasons for hesitancy included vaccine-specific concerns, need for more information, antivaccine attitudes, and lack of trust.
  • The survey was conducted before a vaccine was available and when the pandemic's impact was narrower in the US.

AI-generated from the title and abstract; the full text is not read.

Abstract

BACKGROUND: Coronavirus disease 2019 (COVID-19) has rapidly instigated a global pandemic. Vaccine development is proceeding at an unprecedented pace. Once available, it will be important to maximize vaccine uptake and coverage. OBJECTIVE: To assess intent to be vaccinated against COVID-19 among a representative sample of adults in the United States and identify predictors of and reasons for vaccine hesitancy. DESIGN: Cross-sectional survey, fielded from 16 through 20 April 2020. SETTING: Representative sample of adults residing in the United States. PARTICIPANTS: Approximately 1000 adults drawn from the AmeriSpeak probability-based research panel, covering approximately 97% of the U.S. household population. MEASUREMENTS: Intent to be vaccinated against COVID-19 was measured with the question, "When a vaccine for the coronavirus becomes available, will you get vaccinated?" Response options were "yes," "no," and "not sure." Participants who responded "no" or "not sure" were asked to provide a reason. RESULTS: = 107) did not intend to be vaccinated. Factors independently associated with vaccine hesitancy (a response of "no" or "not sure") included younger age, Black race, lower educational attainment, and not having received the influenza vaccine in the prior year. Reasons for vaccine hesitancy included vaccine-specific concerns, a need for more information, antivaccine attitudes or beliefs, and a lack of trust. LIMITATIONS: Participants' intent to be vaccinated was explored before a vaccine was available and when the pandemic was affecting a narrower swath of the United States. Questions about specific information or factors that might increase vaccination acceptance were not included. The survey response rate was 16.1%. CONCLUSION: This national survey, conducted during the coronavirus pandemic, revealed that approximately 3 in 10 adults were not sure they would accept vaccination and 1 in 10 did not intend to be vaccinated against COVID-19. Targeted and multipronged efforts will be needed to increase acceptance of a COVID-19 vaccine when one becomes available. PRIMARY FUNDING SOURCE: Agency for Healthcare Research and Quality.

The authors' abstract, as published at the source. Annals of Internal Medicine, 2020 · DOI ↗

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Field: Health

HealthSocial Sciences