Pediatric Blood & Cancer· 2026Q1
Integrating Hereditary Hemorrhagic Telangiectasia into the Diagnostic Workup of Adolescent Heavy Menstrual Bleeding
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- Q1SCImago
- 2026year
Short summary
Hereditary Hemorrhagic Telangiectasia (HHT) is an underrecognized cause of heavy menstrual bleeding (HMB) in adolescents and young adults, warranting its inclusion in the differential diagnosis.
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Key points
- Hereditary Hemorrhagic Telangiectasia (HHT) is an underrecognized cause of heavy menstrual bleeding (HMB) in adolescents and young adults.
- HHT should be considered in the differential diagnosis for HMB, especially in patients with suggestive clinical features or family history.
- Stigma associated with menstrual blood loss contributes to a lack of evidence guiding HMB management in individuals with HHT.
AI-generated from the title and abstract; the full text is not read.
Abstract
ABSTRACT To understand the effect of hereditary hemorrhagic telangiectasis (HHT) on uterine bleeding is paramount to improving clinical care of menstruating individuals with HHT. Heavy menstrual bleeding (HMB) in adolescents and young adults (AYAs) with HHT is underrecognized and among individuals with HMB, HHT should be considered in the differential diagnosis, especially among those with suggestive clinical features or family history. Stigmatization associated with vaginal blood loss likely contributes to the paucity of evidence to guide HMB management in individuals with HHT, as previously reported in von Willebrand disease and other inherited bleeding disorders.
The authors' abstract, as published at the source. Pediatric Blood & Cancer, 2026 · DOI ↗
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Field: Genetics (Medicine)
GeneticsMedicine