Science· 2026Q1
A pair of chitosan receptors confer broad-spectrum fungal resistance
- 1citations
- Q1SCImago
- 2026year
Short summary
A receptor complex of apoplast-localized OsFID1 and plasma membrane-localized OsFID2 directly senses chitosan, conferring broad-spectrum fungal resistance in plants.
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Key points
- OsFID1 and OsFID2 form a receptor complex that directly binds chitosan.
- OsFID2 phosphorylation is required for immune activation triggered by chitosan.
- The OsFID1-OsFID2 complex confers broad-spectrum resistance to fungal pathogens.
- OsFID1 homologs are conserved across land plants and show chitosan-binding activity.
- Ectopic expression of OsFID1 in wheat and maize enhanced fungal resistance without growth penalty.
AI-generated from the title and abstract; the full text is not read.
Abstract
Chitosan, a major fungal cell wall component, activates plant immunity, yet the underlying perception mechanism remains unknown. In this study, we identified OsFID1, an apoplast-localized DUF26 domain protein, as a chitosan-binding receptor essential for chitosan-triggered immunity. OsFID1 forms a receptor complex with OsFID2, a plasma membrane–localized DUF26 receptor-like kinase, to mediate chitosan sensing and immune activation, requiring OsFID2 phosphorylation for function. The OsFID1-OsFID2 complex confers broad-spectrum resistance to fungal pathogens. OsFID1 homologs are conserved in land plants, which show chitosan-binding activity in both monocots and dicots. Ectopic expression of OsFID1 in wheat and maize enhanced fungal resistance without growth penalty. These findings uncover a conserved receptor complex for direct chitosan sensing, advancing our understanding of plant-fungus interactions and providing a potential strategy for engineering durable fungal resistance crops.
The authors' abstract, as published at the source. Science, 2026 · DOI ↗
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Field: Plant Science
Plant ScienceAgricultural and Biological Sciences