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Journal of Endocrinology· 2026Q1

In memory of David J Mangelsdorf: my scientific interactions with Davo

Wen Li Xie

Short summary

This article reflects on scientific interactions with the late David J Mangelsdorf, highlighting his discovery and characterization of retinoid X receptor (RXR) and liver X receptor (LXR).

AI-generated from the title and abstract; the full text is not read.

Key points

  • David J Mangelsdorf, a senior colleague in nuclear receptors, passed away in 2025.
  • The author shared a postdoctoral mentor with Dr. Mangelsdorf at the Salk Institute.
  • The article discusses scientific interactions and research collaborations with Dr. Mangelsdorf.
  • Mangelsdorf's discovery and characterization of RXR and LXR receptors are highlighted for their impact.

AI-generated from the title and abstract; the full text is not read.

Abstract

Abstract David J Mangelsdorf was a senior colleague in the field of nuclear receptors who passed away unexpectedly in 2025. Dr Mangelsdorf and I share the same postdoctoral mentor at the Salk Institute. This article reflects on my scientific interaction with Dr Mangelsdorf, including the details of our research collaborations and how his discovery and early characterization of retinoid X receptor (RXR) and liver X receptor (LXR) receptor positively influence the research in my laboratory and many other laboratories in the nuclear receptor field.

The authors' abstract, as published at the source. Journal of Endocrinology, 2026 · DOI ↗

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Field: History

HistoryArts and Humanities