Orthopedic Reviews· 2026Q2
Preoperative Factors Associated With Pulmonary Embolism Following Primary Total Hip Arthroplasty: An ACS-NSQIP Analysis of 2017–2021 Data
- 0citations
- Q2SCImago
- 2026year
Short summary
Disseminated cancer (OR 6.44), steroid use (OR 1.69), female sex (OR 1.23), older age (OR 1.041/year), and higher BMI (OR 1.031/kg/m²) were associated with 30-day pulmonary embolism (PE) after primary total hip arthroplasty in a Q2 journal analysis of nearly 200,000 patients.
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Key points
- Disseminated cancer (OR 6.44), steroid use (OR 1.69), female sex (OR 1.23), age (OR 1.041/year), and BMI (OR 1.031/kg/m²) are associated with 30-day PE after primary total hip arthroplasty.
- The study analyzed 196,495 complete cases from ACS-NSQIP data (2017–2021).
- The identified PE risk factors resulted in a modest predictive discrimination (AUC 0.647).
- The model showed calibration limitations (Hosmer–Lemeshow P = .012) and requires validation.
AI-generated from the title and abstract; the full text is not read.
Abstract
Background This study examined preoperative factors associated with 30-day pulmonary embolism (PE) after primary total hip arthroplasty. Methods ACS-NSQIP records from 2017–2021 with CPT code 27130 were analyzed. Complete cases were included using cleaned body mass index (BMI), age, sex, steroid use, and disseminated cancer. These five variables were entered jointly into logistic regression. Results Among 196,495 complete cases, 484 (0.246%) had PE. Adjusted odds ratios were 6.44 for disseminated cancer, 1.69 for steroid use, 1.23 for female sex, 1.041 per year of age, and 1.031 per kg/m² of BMI (all P < .05). Apparent AUC was 0.647 (95% CI, 0.622–0.672). The Hosmer–Lemeshow test indicated lack of fit (P = .012). Conclusions Five preoperative characteristics were associated with PE. Discrimination was modest, calibration limitations were present, and validation is required before clinical use.
The authors' abstract, as published at the source. Orthopedic Reviews, 2026 · DOI ↗
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Field: Internal Medicine
Internal MedicineMedicine