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Lasers in Medical Science· 2026Q2

Interpreting corneal changes after PRK: Integrating biomechanics with tomographic remodeling

Murat Kaşıkçı, Göksu Alaçamlı, Konuralp Yakar

Short summary

Corneal biomechanical and tomographic measurements change after PRK, but current data from separate cohorts and observation periods prevent establishing a common postoperative trajectory or confirming benignity of abnormal results.

AI-generated from the title and abstract; the full text is not read.

Key points

  • PRK alters corneal biomechanical and tomographic measurements.
  • Current data from separate cohorts and observation periods are insufficient to establish a common postoperative trajectory.
  • It is unclear if abnormal index classifications after PRK are benign in individual eyes.
  • Prospective, paired measurements with Pentacam and Corvis ST are needed to develop postoperative references.

AI-generated from the title and abstract; the full text is not read.

Abstract

Photorefractive keratectomy (PRK) alters corneal biomechanical and tomographic measurements, but postoperative change, an abnormal index classification, and progressive ectasia are distinct. Saif et al. reported biomechanical changes at 6 months; a separate Pentacam cohort showed tomographic changes at 1 month. Clinically and topographically normal eyes assessed approximately 25 years after PRK also had frequent abnormal classifications. These different cohorts and observation periods cannot establish a common postoperative trajectory or show that an abnormal result is benign in an individual eye. Prospective paired Pentacam and Corvis ST measurements in the same eyes, followed by independent validation, are needed to develop postoperative references. Until then, serial clinical and tomographic findings should inform interpretation of isolated index abnormalities.

The authors' abstract, as published at the source. Lasers in Medical Science, 2026 · DOI ↗

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Field: Radiology, Nuclear Medicine and Imaging

Radiology, Nuclear Medicine and ImagingMedicine