ACS Omega· 2026Q1
Selective Hg2+ Detection Using an Aza-BODIPY-Derived NIR Fluorescence Sensor: Environmental and Biological Applications
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- Q1SCImago
- 2026year
Short summary
A novel aza-BODIPY derivative (BT) acts as a "turn-on" NIR fluorescent sensor for Hg2+, achieving a 1.7 ppb detection limit and enabling reversible sensing with KI.
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Key points
- A novel aza-BODIPY derivative (BT) functions as a "turn-on" NIR fluorescent sensor for Hg2+.
- The sensor achieves a detection limit of 1.7 ppb in H2O:EtOH (3:7 v/v).
- Sensing is selective and reversible with the addition of potassium iodide (KI).
- BT was successfully applied to quantify Hg2+ in environmental water and fertilizer samples.
- BT enabled Hg2+ bioimaging in human liver cancer cells with low cytotoxicity.
AI-generated from the title and abstract; the full text is not read.
Abstract
Abstract Mercury contamination in natural environments poses severe threats to ecosystems and human health, emphasizing the urgent need for reliable Hg2+ detection methods. In this work, a novel near-infrared (NIR) fluorescent aza-BODIPY derivative (BT) was synthesized as a potential fluorescence sensor. BT exhibited dual colorimetric and “turn-on” NIR fluorometric responses toward Hg2+ in H2O:EtOH (3:7 v/v), achieving a detection limit of 1.7 ppb. The sensor displayed high selectivity through rapid BT–Hg2+ complexation, with reversible sensing enabled by the addition of potassium iodide (KI). Practical applicability was demonstrated by quantifying Hg2+ in environmental water and fertilizer samples. BT-based paper test strips provided a specific colorimetric response for Hg2+, while bioimaging in human liver cancer cells revealed effective visualization with low cytotoxicity. Collectively, these findings establish BT as a versatile and reliable platform for Hg2+ detection, offering significant promise for environmental monitoring and sustainable health protection.
The authors' abstract, as published at the source. ACS Omega, 2026 · DOI ↗
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Field: Spectroscopy
SpectroscopyChemistry