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Emerging infectious diseases· 2026Q1

Disseminated Trimethoprim/Sulfamethoxazole–Resistant Nocardiosis in Renal Transplant Recipient, India

Sandeep Rao Kordcal, Md Tariq Maula, Vivek Malleshappa Suguna, Adil Rashid Khan et al.

Short summary

A renal transplant recipient in India developed disseminated nocardiosis caused by trimethoprim/sulfamethoxazole-resistant Nocardia, despite receiving this drug as prophylaxis.

AI-generated from the title and abstract; the full text is not read.

Key points

  • A renal transplant recipient on trimethoprim/sulfamethoxazole prophylaxis developed disseminated nocardiosis.
  • The Nocardia strain was resistant to trimethoprim/sulfamethoxazole, indicating a treatment failure despite prophylaxis.
  • The patient also had pulmonary aspergillosis.
  • Complete clinical and radiological resolution was achieved with alternative antimicrobial therapy after 6 months.

AI-generated from the title and abstract; the full text is not read.

Abstract

A renal transplant recipient in India receiving trimethoprim/sulfamethoxazole prophylaxis experienced fever, hemoptysis, and neurologic deficits. The diagnosis was pulmonary aspergillosis and disseminated nocardiosis caused by trimethoprim/sulfamethoxazole-resistant Nocardia. Antimicrobial drug therapy led to complete clinical and radiological resolution after 6 months. This case highlights a resistant breakthrough Nocardia pathogen in a transplant recipient.

The authors' abstract, as published at the source. Emerging infectious diseases, 2026 · DOI ↗

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Field: Microbiology

MicrobiologyMedicine