iScience· 2026Q1
Low-cost geometry-tunable PDMS intraocular lenses fabricated using LCD 3D-printed molds for canine ophthalmic applications
- 1citations
- Q1SCImago
- 2026year
Short summary
A novel method uses inexpensive LCD 3D-printed molds to cast geometry-tunable polydimethylsiloxane (PDMS) intraocular lenses (IOLs) with optical power ranging from 18 to 42 D, achieving dimensional accuracy below 1.5%.
AI-generated from the title and abstract; the full text is not read.
Key points
- Developed a reusable mold fabrication strategy using PMMA barrier layers to overcome PDMS curing inhibition.
- Fabricated PDMS IOL prototypes with a 6 mm optic and dimensional deviation below 1.5%.
- Achieved optical power tunability from 18 to 42 D by varying mold curvature.
- Demonstrated IOLs with >95% visible-light transparency, comparable focusing ability to commercial IOLs, and acceptable cytocompatibility.
AI-generated from the title and abstract; the full text is not read.
Abstract
This study demonstrates the feasibility of fabricating geometry-tunable polydimethylsiloxane (PDMS) intraocular lens (IOL) prototypes using consumer-grade liquid crystal display (LCD) 3D-printed molds and PDMS casting. A reusable mold fabrication strategy incorporating a PMMA barrier layer successfully eliminated PDMS curing inhibition while preserving the mold geometry for repeated casting. The fabrication workflow accurately replicated a plate-haptic lens with a 6 mm optic and dimensional deviation below 1.5%, while enabling optical power to be tuned from 18 to 42 D by varying mold curvature alone. The fabricated PDMS IOLs exhibited high visible-light transparency (>95%), preliminary focusing ability, resolving power and image contrast comparable to a commercial IOL, acceptable post-treatment cytocompatibility, successful injector-assisted delivery with recovery of the original geometry, and preliminary hydrolytic stability and leachability performance. These results establish a reproducible, low-cost, and customizable fabrication platform for PDMS intraocular lenses and provide a foundation for future optimization toward customizable veterinary ophthalmic applications.
The authors' abstract, as published at the source. iScience, 2026 · DOI ↗
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Field: Biomedical Engineering
Biomedical EngineeringEngineering