Annals of the Academy of Medicine Singapore· 2026Q2
Temporal trends of migraine and tension‑type headache in adolescents across China, Germany and the US
- 2citations
- Q2SCImago
- 2026year
Short summary
Adolescent migraine and tension-type headache (TTH) trends diverged across China, the US, and Germany from 1990-2021, with China showing the highest absolute cases and fastest burden growth (migraine AAPC=0.27, TTH AAPC=0.31) despite lower age-standardized rates, while the US/Germany had higher rates but stable/declining trends.
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Key points
- Migraine and TTH trends differed significantly between China and high-SDI nations (US/Germany) in adolescents (10-19 years) from 1990-2021.
- China had the highest absolute cases and fastest burden growth (migraine AAPC=0.27, TTH AAPC=0.31), linked to rapid SDI and academic pressure.
- The US and Germany had higher age-standardized rates but stable/declining trends, benefiting from mature interventions.
- COVID-19 worsened China's burden growth while US/Germany remained stable, amplifying inequalities.
AI-generated from the title and abstract; the full text is not read.
Abstract
Abstract Background Adolescence (10–19 years) is a critical neurodevelopmental window. This study analyzed temporal trends, disease burden, SDI-related inequalities, and COVID-19 impacts on migraine and tension-type headache (TTH) among 10-19-year-olds in China, USA, and Germany (1990–2021). Methods GBD 2021 data extracted for incidence, prevalence, YLDs by country, age (10–14, 15–19 years), sex. Joinpoint regression for AAPCs of age-standardized rates (ASIR/ASPR/ASYR). Frontier analysis, SII, CI assessed SDI associations/inequalities. Results Trends diverged: China had the highest absolute cases but lowest ASRs (migraine AAPC = 0.27, TTH = 0.31); the USA/Germany had higher ASRs but stable declining trends. 10-14-year-olds had more migraine, 15-19-year-olds more TTH. COVID-19 worsened China’s burden growth, while the USA and Germany stayed stable. Conclusion China’s rapid SDI and academic pressure drove fastest burden growth; high-SDI nations benefited from mature interventions. COVID-19 amplified inequalities. Priorities: China: school headache screening; USA: expand telehealth for uninsured youth; Germany: scale stress management programs.
The authors' abstract, as published at the source. Annals of the Academy of Medicine Singapore, 2026 · DOI ↗
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Field: Neurology (Medicine)
Clinical NeurologyMedicine