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Discover Chemistry.· 2025· Review

Reactive oxygen species (ROS): sources, generation, disease pathophysiology, and antioxidants

Waseem Ahmad Ansari, Kajal Srivastava, Malik Nasibullah, Mohammad Faheem Khan

Short summary

This review details the dual role of reactive oxygen species (ROS): beneficial at low concentrations for cellular regulation, but destructive at high levels, leading to diseases like cancer and diabetes. It covers ROS sources, molecular mechanisms of generation, and the role of various endogenous and exogenous antioxidants in scavenging them.

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