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Cochrane Database of Systematic Reviews· 2026· Review

Pharmacotherapy for post traumatic stress disorder (PTSD)

Taryn Williams, Nicole Phillips, Dan J. Stein, Jonathan Ipser

Short summary

Selective serotonin reuptake inhibitors (SSRIs) improve PTSD symptoms, with 58% of participants responding compared to 35% on placebo, based on moderate-certainty evidence from 66 RCTs (7442 participants).

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Field: Clinical Psychology

Clinical PsychologyPsychology