eLife· 2026Q1

In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles

Zahra Seraj, Ximena Zottig, Chun‐Ying Huang, A.B. Loveland et al.

4citations
Q1SCImago
2026year

Short summary

In extracto cryo-EM achieved ~2.2 Å resolution maps of mammalian ribosomes, revealing elongation factor 2 (eEF2) bound to >95% of hibernating ribosomes and unexpectedly on 60S subunits.

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Structural BiologyBiochemistry, Genetics and Molecular Biology