Analytical Chemistry· 2026Q1
Enzymatic Ligation Strategy to Enhance Electrospray Ionization Efficiency and Liquid Chromatography─Mass Spectrometry of DNA and RNA Oligonucleotides
- 0citations
- Q1SCImago
- 2026year
Short summary
A novel enzymatic ligation strategy uses short, decyl-functionalized DNA oligonucleotides to enhance RNA mass spectrometry (MS) signal by an average of 2.1-fold, improving sensitivity and liquid chromatography retention.
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