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Analytical Chemistry· 2026Q1

Fe–N 3 S Single-Atom Nanozyme with Asymmetric Coordination for Ultra-Low-Background Colorimetric Immunoassays

Yu Zheng, Mingdi Xu, Mingdi Xu, Man Xu et al.

Short summary

A novel Fe–N 3 S single-atom nanozyme with asymmetric coordination exhibits high peroxidase-like activity (26.82 U mg –1 ) and significantly lower oxidase-like activity (0.018 U mg –1 ), enabling an ultra-low-background colorimetric immunoassay for CD40L detection with a limit of detection of 0.69 pg mL –1 .

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Field: Materials Chemistry

Materials ChemistryMaterials Science