Cancer Science· 2026Q1

EPHX2 Loss Promotes CRC Migration via EET ‐Dependent Chemokine Elevation and Mitochondrial Defect

Jianjun Zhu, Jingjia Chang, Zhiyong Li, Jin Wu et al.

0citations
Q1SCImago
2026year

Short summary

Loss of Epoxide hydrolase 2 (EPHX2) in colorectal cancer (CRC) promotes cell migration by increasing chemokines (CXCL) and impairing mitochondrial biogenesis through EET accumulation.

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BiochemistryBiochemistry, Genetics and Molecular Biology