Journal of Personalized Medicine· 2026Q1

Impact of Cytochrome P450 and P-glycoprotein Gene Polymorphisms on the Risk of Hemorrhagic Complications in Older Patients with Non-Valvular Atrial Fibrillation Treated with Rivaroxaban

I. V. Sychev, A. P. Kondrakhin, Sh. P. Abdullaev, П. О. Бочков et al.

0citations
Q1SCImago
2026year

Short summary

The ABCB1 rs1045642 (C3435T) polymorphism is associated with a 2.42-fold increased risk of hemorrhagic complications in older patients (mean age 83.2) treated with rivaroxaban, with the CC genotype showing higher bleeding propensity.

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PharmacologyPharmacology, Toxicology and Pharmaceutics