Nature Communications· 2026Q1

Dual effect of α-synuclein disease variants on condensate formation

Aswathy Chandran, Aishwarya Agarwal, Tianhao Wang, Leslie Amaral et al.

1citations
Q1SCImago
2026year

Short summary

Two Parkinson's disease-associated α-synuclein variants (E46K and E83Q) enhance biomolecular condensate formation, while others (A30G, G51D, A53E) fail to form them.

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Field: Neurology (Medicine)

NeurologyMedicine