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American Journal of Physical Medicine & Rehabilitation· 2026Q1

Clinical Practice Audit of 60-day Temporary Peripheral Nerve Stimulation

David Sherwood, Oishi Paul, R. Sterling Haring

Short summary

A 60-day temporary peripheral nerve stimulation (PNS) protocol provided at least 50% pain relief in 48% of patients at 2 weeks, but this benefit diminished significantly over time, with no patients reporting this level of relief at 14 months.

AI-generated from the title and abstract; the full text is not read.

Key points

  • 48% of patients reported ≥50% pain relief at 2 weeks after 60-day temporary PNS.
  • Pain relief decreased significantly over time: 33.3% at 2 months, 15.7% at 5 months, and 3.9% at 11 months.
  • No patients reported ≥50% pain relief at 14 months post-implantation.
  • The study included 102 patients with chronic pain in a real-world setting.

AI-generated from the title and abstract; the full text is not read.

Abstract

OBJECTIVE: To prospectively evaluate pain relief and functional outcomes through 14 months after 60-day percutaneous peripheral nerve stimulation (PNS) in a consecutive real-world cohort. DESIGN: Prospective single-center observational cohort study of 102 consecutive patients implanted with 60-day temporary percutaneous PNS for chronic pain. Outcomes were collected at 2 weeks and 2, 5, 8, 11, and 14 months. The principal outcome measure was the proportion reporting ≥50% pain relief at each follow-up interval. Secondary outcomes included ≥80% pain relief, numeric pain rating scale (NRS), Brief Pain Inventory item 9a (BP-9a), Oswestry Disability Index, Patient Global Impression of Change (PGIC), and adverse events. RESULTS: ≥50% pain relief was reported by 49/102 (48.0%; 95% CI, 38.0-58.2%) at 2 weeks, 34/102 (33.3%; 95% CI, 24.3-43.4%) at 2 months, 16/102 (15.7%; 95% CI, 9.2-24.2%) at 5 months, 10/102 (9.8%; 95% CI, 4.8-17.3%) at 8 months, and 4/102 (3.9%; 95% CI, 1.1-9.7%) at 11 months. At 14 months, no participants met the ≥50% threshold (0/4 observed case; 0/102 under the fixed-denominator framework). CONCLUSIONS: In this heterogeneous real-world cohort, 60-day temporary PNS produced short-term benefit in a subset of patients, but durable post-explant response was uncommon.

The authors' abstract, as published at the source. American Journal of Physical Medicine & Rehabilitation, 2026 · DOI ↗

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Field: Anesthesiology and Pain Medicine

Anesthesiology and Pain MedicineMedicine