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Journal of Clinical Investigation· 2026Q1

UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice

Bingge Zhang, Ye He, Ting Su, Xiaomei Li et al.

Short summary

A new drug, UA-30, extended lifespan and improved motor function in ALS mice by enhancing mitophagy through RalA inhibition.

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Field: Neurology (Medicine)

NeurologyMedicine