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ACS Omega· 2026Q1

Evaluation of Passiflora edulis Seed Extract and Piceatannol in Attenuating Hyperglycemia and Oxidative Stress Using Human and Nonhuman Antidiabetic Enzymes, Human Neutrophil Oxidative Burst, and Embryonic Zebrafish Hyperglycemia Model

Elaine L. S. S. Mendonça, Ana Ramalho, Boniek G. Vaz, Alane C. M. Oliveira et al.

Short summary

Passiflora edulis seed extract (PESE) and its compound piceatannol (PIC) significantly reduce hyperglycemia and oxidative stress via multiple mechanisms, with PESE showing lower embryotoxicity than PIC.

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Field: Complementary and alternative medicine

Complementary and alternative medicineMedicine