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mSystems· 2026Q1

Phylogenetic inconsistency of pairwise SNP clustering for inferring tuberculosis transmission in a high-burden, endemic setting: a case study from Thailand

Pakorn Aiewsakun, Walter S. Hunter, Prasit Palittapongarnpim

Short summary

Pairwise SNP-distance clustering, a common method for inferring tuberculosis transmission, frequently generates non-monophyletic clusters in high-burden, endemic settings like Thailand, unlike in low-burden settings like the UK.

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Field: Infectious Diseases

Infectious DiseasesMedicine