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Biomedicines· 2026Q1

Mechanisms Underlying the Biphasic Effects of Hydrogen Sulfide in Rat Intrapulmonary Arteries

Agilė Tunaitytė, Elif Alan, Arnas Aleknavičius, Silvijus Abramavičius et al.

Short summary

Low concentrations of exogenous hydrogen sulfide (H2S) cause contraction in rat intrapulmonary arteries without a significant rise in intracellular calcium, while higher concentrations induce relaxation despite maintained or increased calcium levels, suggesting Ca2+-independent mechanisms.

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BiochemistryBiochemistry, Genetics and Molecular Biology