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Journal of Virology· 2026Q1

Non-neutralizing antibody responses control acute Crimean-Congo hemorrhagic fever virus infection in naïve mice

Kimberly Meade-White, Shanna S. Brown, Samantha Ertl, Natalie McCarthy et al.

Short summary

Non-neutralizing antibody responses, specifically complement-mediated, are critical for controlling acute Crimean-Congo hemorrhagic fever virus (CCHFV) infection in naive mice, with their absence leading to near-uniform mortality in males.

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Field: Infectious Diseases

Infectious DiseasesMedicine