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Chemical Reviews· 2013Q1· Review

Protein Analysis by Shotgun/Bottom-up Proteomics

Yaoyang Zhang, Bryan R. Fonslow, Bing Shan, Moon‐Chang Baek et al.

Short summary

Shotgun/bottom-up proteomics enables comprehensive protein identification and quantification from complex biological samples by digesting proteins into peptides, separating them via liquid chromatography, and analyzing them with mass spectrometry.

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Field: Spectroscopy

SpectroscopyChemistry