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Journal of Chemical Theory and Computation· 2019Q1

Exploration of Chemical Compound, Conformer, and Reaction Space with Meta-Dynamics Simulations Based on Tight-Binding Quantum Chemical Calculations

Stefan Grimme

Short summary

Meta-dynamics simulations using the GFN2-xTB quantum chemistry method can efficiently explore chemical compound, conformer, and reaction spaces, identifying lower energy structures and more complete conformer ensembles with reduced computational effort.

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Field: Spectroscopy

SpectroscopyChemistry