Science· 2020Q1
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
- 3,442citations
- Q1SCImago
- 2020year
Short summary
The crystal structure of the SARS-CoV-2 main protease (Mpro) has been determined, revealing its complex with an improved α-ketoamide inhibitor. This structural insight enables the design of potent Mpro inhibitors with enhanced plasma half-life and lung tropism.
AI-generated from the title and abstract; the full text is not read.
TakeawaysIn the app
Key pointsIn the app
Ask the paperIn the app
The rest is in the Pofolia app
Takeaways, key points and questions to the paper; new summaries every day for your field. Free.
Sign in on the web to openField: Computational Theory and Mathematics
Computational Theory and MathematicsComputer Science