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Journal of Medicinal Chemistry· 2014Q1

Rings in Drugs

Richard D. Taylor, Malcolm MacCoss, Alastair D. G. Lawson

Short summary

Analysis of FDA Orange Book drugs reveals only 351 ring systems and 1197 frameworks, with an average of six new ring systems entering drug space annually, and 83% of frequently used systems predating 1983.

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Field: Computational Theory and Mathematics

Computational Theory and MathematicsComputer Science