Science· 2013Q1

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko, Takahiro Seki et al.

2,232citations
Q1SCImago
2013year

Short summary

The cellular thermal shift assay (CETSA) enables monitoring of drug binding to target proteins directly within cells and tissues, overcoming previous limitations in drug development.

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Field: Computational Theory and Mathematics

Computational Theory and MathematicsComputer Science