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Nucleic Acids Research· 2022Q1

CB-Dock2: improved protein–ligand blind docking by integrating cavity detection, docking and homologous template fitting

Yang Liu, Xiaocong Yang, Jianhong Gan, Shuang Chen et al.

Short summary

CB-Dock2, a new blind docking server, integrates cavity detection, docking, and homologous template fitting to achieve ~85% success rate in binding pose prediction (RMSD < 2.0 Å), outperforming its predecessor and other popular tools.

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Field: Computational Theory and Mathematics

Computational Theory and MathematicsComputer Science