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The American Journal of Surgical Pathology· 2026Q1

Widespread Loss of Heterozygosity and Endoreduplication in Odontogenic Myxoma

Ivan J. Stojanov, Melad N. Dababneh, Vincent Cracolici, Sana Qureshi et al.

Short summary

All 7 odontogenic myxoma (OM) tumors studied showed widespread loss of heterozygosity (LOH), with 5 exhibiting near-haploid genomes and 2 showing pseudo-hyperdiploidy due to endoreduplication, suggesting LOH is a recurrent molecular signature.

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Field: Oral Surgery

Oral SurgeryDentistry