Biomedicines· 2026Q1

Calcineurin Inhibitor-Based Triple Immunosuppressive Therapy Induces Profibrotic Changes in the Jejunal Mucosa of Male Rats: A Digital Image Analysis of Collagen Fibers

Kamila Szumilas, Aleksandra Wilk, Paweł Szumilas, Karolina Klimek et al.

0citations
Q1SCImago
2026year

Short summary

Six months of triple immunosuppressive therapy (cyclosporine A or tacrolimus with rapamycin and prednisone) increased collagen fiber deposition in male rat jejunal mucosa by 30% compared to controls, with cyclosporine showing the highest increase.

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