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The Journal of Organic Chemistry· 2026Q2

Synthesis, Photophysical Properties, and Ab Initio Calculations of 2-(2-Hydroxy/methoxyphenyl)pyrimidines Substituted by Sterically Hindered Electron-Donating Groups

Clément Diguet, Angela Dellai, Adèle D. Laurent, Julien Massue et al.

Short summary

Methoxy-substituted pyrimidines with bulky electron-donating groups exhibit tunable fluorescence, with NPh2 derivatives showing the highest quantum yields, driven by steric effects and twisted geometries that balance charge transfer and proton transfer pathways.

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Field: Physical and Theoretical Chemistry

Physical and Theoretical ChemistryChemistry