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Nature Microbiology· 2026Q1

Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses

Peng Liu, Qianhui Zhu, Jingyi Liu, Zhixing Ma et al.

Short summary

Hedgehog aminopeptidase N (APN) is identified as the functional receptor for European and Asian hedgehog merbecoviruses (EriCoVs), with a distinct binding mode compared to other coronavirus families.

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Animal Science and ZoologyAgricultural and Biological Sciences