PofoliaShared via Pofolia

Clinical Genetics· 2026Q2

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy

Tameemi Abdalla Moady, Hadar Hulin Ma'ayan, Michal Cohen, Karin Weiss

Short summary

A homozygous splice-site variant in PIP5K1C caused lethal congenital contracture syndrome 3 (LCCS3) in a newborn, who also presented with hyperinsulinemic hypoglycemia and optic atrophy, expanding the known phenotype of this rare disorder.

AI-generated from the title and abstract; the full text is not read.

TakeawaysIn the app
Key pointsIn the app
Ask the paperIn the app

The rest is in the Pofolia app

Takeaways, key points and questions to the paper; new summaries every day for your field. Free.

Sign in on the web to open

Field: Genetics

GeneticsMedicine