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BMC Biology· 2026Q1

Foxn1 regulates epidermal structure, redox balance, and age related changes

Sylwia Machcińska, Marta Kopcewicz, Joanna Wiśniewska, Karla Valdivieso et al.

Short summary

Foxn1 deficiency in mice (Foxn1+/-) leads to thinner epidermis, thicker dermis, disrupted keratinocyte differentiation, and altered collagen profiles, suggesting a role in skin aging and repair.

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Field: Dermatology

DermatologyMedicine