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International Journal of Molecular Sciences· 2026Q1

The NSDHL/c-Myc/PKM2 Axis Drives Glycolytic Reprogramming and Tumor Growth in Multiple Myeloma

Can Yue, Bei-Hui Huang, Lin Qi, Xing‐Ding Zhang et al.

Short summary

A novel regulatory axis, NSDHL/c-Myc/PKM2, drives tumor growth in multiple myeloma (MM) by increasing glycolysis, with NSDHL upregulation linked to advanced disease and poor survival.

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Field: Hematology

HematologyMedicine