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CVIR Endovascular· 2026Q2· Review

Intra-arterial lidocaine as a pain management strategy for uterine artery embolisation: a systematic review and meta-analysis

Tarun Haridasan, Abena Kena, Larry Nguyen, K. Tan

Short summary

Intra-arterial lidocaine (IAL) significantly reduced pain at 4 hours and the maximum pain within 24 hours after uterine artery embolisation (UAE) in a meta-analysis of 8 studies (692 patients).

AI-generated from the title and abstract; the full text is not read.

Key points

  • Intra-arterial lidocaine (IAL) significantly reduced pain at 4 hours post-UAE.
  • IAL lowered the maximum pain experienced within the first 24 hours after UAE.
  • No significant differences were observed in pain immediately post-procedure, at 7 or 24 hours.
  • IAL was associated with uncommon serious adverse events.

AI-generated from the title and abstract; the full text is not read.

Abstract

Abstract Post-procedural pain remains a significant challenge following uterine artery embolisation (UAE) and intra-arterial lidocaine (IAL) has emerged as a potential adjunctive analgesic. This systematic review and meta-analysis evaluated the efficacy and safety of IAL during UAE. MEDLINE, Embase, and the Cochrane Library were searched from inception to June 2026, identifying eight studies including 692 patients. IAL significantly reduced pain at 4 h post-procedure and lowered the maximum pain experienced within the first 24 h. However, there were no significant differences in pain immediately after the procedure, at 7 or 24 h, opioid consumption, or inflammatory markers. Serious adverse events were uncommon. These findings suggest that IAL provides meaningful early pain relief and may serve as a safe adjunct in pain management for UAE. Systematic review registration PROSPERO CRD420261428710

The authors' abstract, as published at the source. CVIR Endovascular, 2026 · DOI ↗

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Field: Obstetrics and Gynecology

Obstetrics and GynecologyMedicine