Bioresource Technology· 2015Q1· Review
Pretreatment of lignocellulose: Formation of inhibitory by-products and strategies for minimizing their effects
- 2,093citations
- Q1SCImago
- 2015year
Short summary
Lignocellulose pretreatment, essential for biofuel production, generates inhibitory by-products that hinder microbial and enzymatic processes.
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Key points
- Pretreatment of lignocellulose is a key step for biochemical conversion into biofuels and commodities.
- Pretreatment generates inhibitory by-products from lignocellulose.
- These by-products negatively affect microbial and enzymatic biocatalysts.
- The review covers the formation of these inhibitors and strategies to minimize their effects.
AI-generated from the title and abstract; the full text is not read.
Abstract
Biochemical conversion of lignocellulosic feedstocks to advanced biofuels and other commodities through a sugar-platform process involves a pretreatment step enhancing the susceptibility of the cellulose to enzymatic hydrolysis. A side effect of pretreatment is formation of lignocellulose-derived by-products that inhibit microbial and enzymatic biocatalysts. This review provides an overview of the formation of inhibitory by-products from lignocellulosic feedstocks as a consequence of using different pretreatment methods and feedstocks as well as an overview of different strategies used to alleviate problems with inhibitors. As technologies for biorefining of lignocellulose become mature and are transferred from laboratory environments to industrial contexts, the importance of management of inhibition problems is envisaged to increase as issues that become increasingly relevant will include the possibility to use recalcitrant feedstocks, obtaining high product yields and high productivity, minimizing the charges of enzymes and microorganisms, and using high solids loadings to obtain high product titers.
The authors' abstract, as published at the source. Bioresource Technology, 2015 · DOI ↗
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Field: Biomedical Engineering
Biomedical EngineeringEngineering