PNAS Nexus· 2026Q1
Complementary roles of virtual and real trials in medicine: An interplay of virtuous spirals
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- Q1SCImago
- 2026year
Short summary
Virtual trials offer epistemic opportunities to add mechanistic explainability to the predictive inference of real-world clinical trials.
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Abstract
Abstract Virtual trials provide medical knowledge and practical methods for generating evidence through computational methods. But extending beyond those advantages, they offer epistemic opportunities to add mechanistic explainability to predictive inference of real trials. Relating the distinct contributions and ontology of virtual and real trials enables a transformative convergence of biological and clinical insights that they embody.
The authors' abstract, as published at the source. PNAS Nexus, 2026 · DOI ↗
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